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Cytokinetics, Kairos Scientific, SmithKline Beecham Awarded US Patents

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Cytokinetics has received US Patent No. 6,738,716, “Database system for predictive cellular bioinformatics.” The patent describes a system for acquiring knowledge from cellular information, according to its abstract.

The system has a database comprising a database management module (“DBMS”), as well as a variety of modules, including a population module coupled to the DBMS for categorizing and storing a plurality of features (e.g., cell size, distance between cells, cell population, cell type) from an image acquisition device into the database, the abstract states.

In addition, the system has a translation module coupled to the DBMS for defining a descriptor from a set of selected features from the plurality of features. In a specific embodiment, the descriptor is for a known or unknown compound, e.g., a drug. A prediction module is coupled to the DBMS for selecting one of a plurality of descriptors from known and unknown compounds from the database based upon a selected descriptor from a selected compound. The selected compound may be one that is useful for treatment of human beings or the like, the abstract states.


Kairos Scientific has received US Patent No. 6,738,502, “Multispectral taxonomic identification.” The patent describes an invention that provides an instrument and methods for a multispectral optical technique that can simultaneously classify individual biological cells within mixed populations, according to the abstract.

Furthermore, the invention, known as Multispectral Taxonomic Identification (MTID), shows that microscopy can be combined with a software analysis program to measure and categorize the fluorescence and other spectroscopically identifiable signals from complex populations of cells in situ, without cultivation. The invention thus enables high-throughput screening of cells for taxonomic classification, the abstract states.


SmithKline Beecham has received US Patent No. 6,740,756, “Fluorescent lanthanide chelates.” The patent describes an invention that provides complexing agents of Formula I ##STR1## which contain novel photosensitizers and produce long-lived fluorescence for use in bioaffinity assays, especially HTRF (homogeneous time-resolved fluorescence) assays, according to the abstract.

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