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Corning, Cellomics, and Boston University Among US Patent Recipients


Corning has been awarded US Patent No. 6,767,607, “Multiwell plate having transparent well bottoms.”

Inventors listed on the patent are: Allison Tanner, Gregory Martin, and Hongming Wang.

According to its abstract, the patent describes a multiwell plate that is used for assaying samples and is made from a plastic upper plate which forms the sidewalls of one or more wells and a glass lower plate which forms the bottom walls of the wells. The plastic upper plate and glass lower plate are attached and bound to one another by an enhanced adhesive that … strengthens a bond between the plates, the abstract states. The patent also describes methods for making such multiwell plates.

Cellomics has been awarded US Patent No. 6,768,982, “Method and system for creating and using knowledge patterns.”

Inventors listed on the patent are: Mark Collins, John Shaw, and Ricardo Colasanti.

According to its abstract, the patent describes a method and system for creating and using knowledge patterns, where one or more patterns derived from one or more pharmaceutical data sources are acquired. A knowledge map is created using the one or more patterns … and is used for recognizing previously unseen or unknown patterns from large amounts of pharmaceutical data obtained by automated screening systems, the abstract states. The method and system may be used to locate and describe previously unrecognized patterns of biological or chemical activity concealed within a selected range of drug discovery data, the abstract states. This may improve the identification, selection, validation, and screening of new real or virtual pharmaceutical compounds, the abstract states.

Boston University has been awarded US Patent No. 6,762,036, “Cellular physiology workstations for automated data acquisition and perfusion control.”

Inventors listed on the patent are: David Farb, Nader Yaghoubi, and Terrell Gibbs.

According to its abstract, the patent describes a cellular physiology workstation for automated data acquisition and perfusion control, that can be used for physiological and electrophysiological experiments. The patent also discloses methods for employing such a workstation in physiological and electrophysiological experiments. The workstation comprises on or more recording chambers, each for holding one or more cells to be measured, the abstract states. Perfusion means, such as an automatic perfusion system, is connected to the recording chamber to perfuse the cells with a plurality of solutions containing a different concentration of one or more agents to be tested, the abstract states. Biosensors, such as patch clamps, electrodes, or microscopes are positioned to detect a response from the cell, the abstract states.

Shi Liu, of Apex, has been awarded US Patent No. 6,767,734, “Method and apparatus for producing age-synchronized cells.”

According to the patent’s abstract, the invention relates to a method and apparatus for producing a cell population of the same chronological age. Cells of a predetermined age are collected onto an array of surfaces, and the collected cells are retained on said surface during their continuous cultivation, and kept from mixing with other descendants by means of flushing away their offspring, the abstract states. Sampling of the array surface at desired times gives cell populations of desired age for examination, assay, and other uses, the abstract states.


The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.