Skip to main content
Premium Trial:

Request an Annual Quote

Corning and Molecular Devices Awarded US Patents

Corning has been awarded US Patent 7,332,328, “Microcolumn-platform based array for high-throughput analysis.”
The inventors listed on the patent are Brian Webb, Jinlin Peng, Michael Brady, Mircea Despa, Keith Horn, Joydeep Lahiri, David Root, James Stamatoff, and Po Ki Yuen.
The patent provides a device and methods for performing biological or chemical analyses, according to the abstract. The device includes an array of three-dimensional microcolumns projecting away from a support plate. As described in the abstract, each microcolumn has a relatively planar, first surface remote from the support plate. An array of multiple, different biological materials may be attached to the first surface. The device, when used in combination with microtiter well plates, can improve the efficiency of high-throughput binding assays that use microarrays.

Molecular Devices has been awarded US Patent 7,332,292, “Constitutively translocating cell line.”
The inventors listed on the patent are Robert Oakley and Christine Hudson.
The patent relates to agonist-independent methods of screening for compounds that alter GPCR desensitization, its abstract said. Included in the invention are cell lines containing GPCR kinases, in which GPCRs are desensitized in the absence of agonist; the GPCR kinases may be modified. The patent also describes methods to determine if a GPCR is expressed at the plasma membrane, and if the GPCR has an affinity for arrestin. Modified GPCRs that have increased arrestin affinity are included in the patent. These modified GPCRs can be used to screen for compounds that alter desensitization, including both the agonist-independent methods and agonist-dependent methods described in the patent.

The Scan

Cell Atlas of Human Lung Development Gives View of Developing Airway

Researchers have generated a cell atlas of human lung development, which they report in Cell.

Study Finds Costs of Genome Sequencing May Limit Utility in Routine Care

Researchers report in the European Journal of Human Genetics that genome sequencing for rare disease diagnoses currently has similar benefits as less expensive exome analysis.

Study Suggests Nursing Mother's Diet Can Impact Offspring's Gut Microbiome

A new Cell Host and Microbe paper finds that mice whose mothers were fed a low-fiber diet during nursing experience lasting microbiota dysbiosis and increased obesity.

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.