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BioImage, Tecan, Pharmacia, and Guava Are Awarded US Patents

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BioImage has been awarded US Patent No. 6,818,443, “Fluorescent proteins.”

Inventors listed on the patent are Ole Thastrup, Søren Tullin, Lars Kongsbak Poulsen, and Sara Petersen Bjørn.

According to its abstract, the patent protects novel variants of the fluorescent protein GFP having improved fluorescent properties.


Tecan has been awarded US Patent No. 6,818,435, “Microfluidics devices and methods for performing cell-based assays.”

Inventors listed on the patent are Bruce Carvalho, Norman Sheppard, Christina Feakes, and Gregory Kellogg.

According to its abstract, the patent provides methods and apparatus for performing microanalytic analyses and procedures, particularly miniaturized cell-based assays. These methods are useful for performing a variety of cell-based assays, including drug candidate screening, life sciences research, and clinical and molecular diagnostics, the abstract states.


Pharmacia and Upjohn has been awarded US Patent No. 6,818,413, “Fluorescence-based high-throughput screening assays for protein kinases and phosphatases.”

Inventors listed on the patent are Dennis Epps and Charles Marschke.

According to its abstract, the patent covers novel fluorescence-based assays for protein kinases and phosphatases that can be used in high-throughput screening. The methods of the invention utilize a competitive immunoassay to determine the amount of substrate that is phosphorylated or dephosphorylated during the course of a kinase or phosphatase reaction to yield a product, as well as the phosphorylating or dephosphorylating activity of a kinase or phosphatase.


Guava has been awarded US Patent No. 6,816,257, “Method and apparatus for detecting microparticles in fluid samples.”

Philippe Goix is the inventor listed on the patent.

According to its abstract, the patent covers a method and apparatus for detecting a fluorescent substance tagged to a microparticle. The device comprises a single-capillary flow carrier system for transporting the microparticle past a selected location, a source of electromagnetic radiation for irradiating the substance tagged to the microparticle, and a detection system for measuring fluorescent light emitted from the substance at the selected location, the abstract states. The method similarly comprises transporting the microparticle to a selected location, irradiating a fluorescent substance tagged to the microparticle, and measuring the fluorescent light emitted from the fluorescent substance at the selected location.

 

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