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Becton Dickinson, GE Healthcare, Caliper Among Recent US Patent Winners

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PrimaGen Holding has been awarded US Patent No. 6,967,016, "Method of determining therapeutic activity and/or possible side-effects of a medicament."

Inventors listed on the patent are Bob van Gemen, Eveline Timmermans, Anthonij de Ronde, and Irene Dobbelaer.

According to its abstract, the patent protects methods for the diagnosis of disease or the determination of functioning of cellular organisms, being of multicellular or unicellular nature, [and] being visible by the naked eye or being a microorganism. The invention provides a method for determining functioning of a cellular organism comprising determining the relative ratio of a first endosymbiont cellular organelle, nucleic acid, and/or gene product thereof, in a sample obtained from the organism, in relation to the amount of a second nucleic acid and/or gene product thereof, the abstract states.


Surface Logix has been awarded US Patent No. 6,967,074, "Methods of detecting immobilized biomolecules."

Inventors listed on the patent are David Duffy, Gregory Kirk, Stewart Campbell, Olivier Schueller, and Melina Agosto.

According to its abstract, the patent protects devices and methods for performing assays on materials, particularly biological materials. The devices and methods make use of self-sealing members, which can be applied to a flat surface to form wells to facilitate immobilization of materials on the surface, then removed to yield a flat surface that facilitates the performance of processes on, and/or detection of, the immobilized material, the abstract states.


Becton Dickinson has been awarded US Patent No. 6,967,086, "Method for determining the presence or absence of respiring cells on a three-dimensional scaffold."

Inventors listed on the patent are David Guarino, John Hemperly, Catherine Spargo, Andrea Liebmann-Vinson, Mohammad Heidaran.

According to its abstract, the patent protects a method and apparatus for determining the presence or absence of respiring cells, involving combining a three-dimensional biomimetic scaffold and cells onto a sensor composition.


Amersham Biosciences (GE Healthcare) has been awarded US Patent No. 6,967,250, "Energy transfer dyes."

Inventors listed on the patent are Shiv Kumar, Satyam Nampalli, and Mahesh Khot.

According to its abstract, the patent protects energy transfer dyes, their preparation, and their use as labels in biological systems. The dyes are preferably in the form of cassettes, which enable their attachment to a variety of biological materials. The dyes and the reagents that can be made from them offer a wide variety of fluorescent labels with large Stokes' shifts enabling their use in a variety of fluorescence applications over a wide range of the visible spectrum, the abstract states.


Caliper Life Sciences has been awarded US Patent No. 6,967,489, "Method and apparatus for controllably effecting samples using two signals."

Inventors listed on the patent are Carlton Brooks, Morten Jensen, and Seth Stern.

According to its abstract, the patent protects methods and systems for effecting a parameter and detecting a parameter using two electric signals in a conductive path.

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