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Beckman Coulter, Cellomics, Cisbio, PerkinElmer, and Tecan


Following is an initial list of new products for high-content screening and cell-based assays launched at the

Society for Biomolecular Screening Conference

, being held through Sept. 15 in Orlando, Fla. For a full list of new products introduced at the show, as well as a conference recap, please see next week’s issue of Inside Bioassays.

Beckman Coulter

Beckman Coulter introduced the BioMek Assay Workstation, which is optimized for cell-based screening and ELISA assays. The workstation can be configured with either the Biomek FX or NX liquid handlers, and provides multiple pipetting and configuration options for different capacity, throughput, and lab space requirements, the company said.


Cellomics released a new image analysis software module called the Spot Detector BioApplication. The image analysis software is designed to work with Cellomics’ high-content screening instrumentation, including the ArrayScan VTI, and ArrayScan versions 3.1 and 4.0. It is an image analysis algorithm that allows researchers to scan and analyze a 96-well plate in as little as five minutes, Cellomics said.

In addition, Cellomics announced the CellSelect rental plan, which allows Cellomics customers to rent BioApplication software modules on an as-needed basis, at a significantly reduced first-year cost as compared to purchasing the modules.


Cisbio announced the availability of the HTRF-based Cyclic GMP assay kit. Based on the company’s proprietary HTRF technology, the assay was developed to measure cGMP levels in cells and, more specifically, to monitor both soluble and particulate guanylyl cyclase activity.

Cisbio also launched its HTRF-based Cyclic AMP assay kit. This is a homogenous, single-step, competitive immunoassay based on the interaction between europium cryptate-labeled, anti-cAMP antibody and cAMP-XL665 conjugates.


PerkinElmer launched 19 new products at the conference, several of which have applications in HCS and cell-based screening:

• The CellLux uHTS Cellular Screening System features fiber-optic imaging and integrated liquid handling for high- throughput, live-cell “inject and read” applications, and is ideal for ion-channel screening, the company said.

• The Cellular Workstation is a fully integrated and automated workstation for conducting live- cell screening.

• The CellEx poly-D-lysine coated microplates are used to anchor live cells onto a microplate for cellular applications, particularly viewing with the CellLux.

• The ATP-Lite One-step, a high- throughput live cell assay for evaluating compound toxicity on live cells.


Tecan launched the Freedom EVO96R and EVO384R, multi-channel pipetting platforms for rapid sample dispensing and microplate processing for genomics, proteomics, and drug-discovery applications. EVO96R is a 96-channel platform or medium- to high-throughput pipetting in the range of one to 200 microliters. The EVO384R dispenses into 384-well plates and is ideal for medium- to high-throughput applications that demand a broad volume range, such as 200 nanoliters to 50 microliters, Tecan said. Both platforms are controlled by Tecan’s Freedom Evoware software.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.