Investigators at the Baylor College of Medicine have developed a high-throughput microscopy technique that has enabled them to quantify androgen receptor subcellular and subnuclear distribution and transcriptional reporter-gene activity on a cell-by-cell basis.
 
Simultaneous analysis of DNA content allowed them to determine cell cycle position and enabled them to analyze cell cycle-dependent changes in androgen receptor function in unsynchronized cell populations.
 

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