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Aurora Discovery, Beckman Coulter, ThermoElectron, Tecan, and Genetix Group

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Aurora Discovery last week announced the availability of three new products: the NanoRaptr and BioRaptr FRD liquid handler workstations for non-contact handling of cells, protein solutions, DMSO solutions, and viscous solutions into low-volume microplates; and the ChemLib 1,536- and 3,456-well microplates for low-volume drug discovery, genomics, and proteomics research.


Beckman Coulter has introduced the Biomek FX ADME/Tox Workstation for in vitro drug permeability measurements. The new platform automates the Parallel Artificial Membrane Permeability Analysis method for the determination of passive absorption of a drug candidate through an artificial lipid membrane.


ThermoElectron last week announced the launch of the LeadStream ADME/Tox platform for conducting early-stage drug compound assessments. The platform comprises Orchestrator software for collecting and reporting ADME/Tox data; Reformatter software for online preparation of plates; WorkCell fully automated assay platform; and LC/MS analysis and quantification.


Tecan last week announced the availability of several drug-discovery products, including the Freedom EVO96R multi-channel sample dispensing and microplate processing platform for procedures in genomics, proteomics, sample preparation, compound management, and high-content screening; the LabCD ADME/Tox Evo System, which integrates the LabCD-96 microfluidics disc for a complete ADME/Tox assay platform; the Safire2 monochromator microplate reader for time-resolved fluorescence resonance energy transfer assays based on terbium; and Cellerity, a fully automated high-throughput system for cell and protein production.


Genetix Group has launched the ClonePixFL instrument for mammalian cell imaging and picking. The ClonePixFL adds fluorescent capabilities to Genetix’s existing ClonePix platform.

 

The Scan

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.

Study Reveals Potential Sex-Specific Role for Noncoding RNA in Depression

A long, noncoding RNA called FEDORA appears to be a sex-specific regulator of major depressive disorder, affecting more women, researchers report in Science Advances.

New mRNA Vaccines Offer Hope for Fighting Malaria

A George Washington University-led team has developed mRNA vaccines for malaria that appear to provide protection in mice, as they report in NPJ Vaccines.

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.