AnaSpec last week announced the introduction of its SensoLyte 390 ACE2 activity assay kit, which the company said is the industry's first assay kit for the continuous monitoring of ACE2 activity.
The SensoLyte 390 assay kit uses a Mc-Ala/Dnp fluorescence resonance energy transfer peptide for the high throughput screening of ACE2 inhibitors and inducers, and for the continuous assay of ACE2 activity.
In the intact FRET peptide, the fluorescence of Mc-Ala is quenched by Dnp. Upon cleavage into two separate fragments by ACE2, the fluorescence of Mc-Ala is recovered, and can be monitored at excitation/emission of 330/390nm.
Performed in a 96-well microplate, the assay can detect the activity of subnanogram levels of ACE2.
Thermo Fisher Scientific this week announced that it has incorporated Data Manager into its Nautilus LIMS version 8.0. Thermo Scientific Nautilus can now capture, archive, and store both derived and raw instrument data, permitting users instant access and manipulation of the data without the original software.
Data Manager is a complete storage and retrieval system that understands and preserves analytical data, documents, and PDF (Portable Document Format) files. It is able to view, search, and manipulate real data and its metadata without the original application.
Thermo Scientific Nautilus 8.0 has been designed to give scientists a comprehensive instrument-unified view of all relevant data directly from the LIMS rather than at the lab bench via multiple software packages. Drawing on technology from Thermo Scientific’s GRAMS Suite, the Data Manager module converts instrument data to a vendor neutral XML (eXtensible Mark-up Language) format and allows automatic linking to LIMS entities for instant investigation of suspect results.
Using a converter library of over 150 file formats, instrument data can be translated into a platform-neutral XML that enables it to be retrieved and visualized on virtually any platform, with no reliance on the original instrument software. In binding these converted XML files to LIMS entities, Nautilus 8.0 with Data Manager provides companies with the ability to share, compare, query, and visualize analytical data, with or without the original instrument hardware/software.
This advanced data management functionality is available as standard upon installation or as an upgrade to Nautilus LIMS version 8.0. Customers only need to purchase the appropriate converter library for their instrumentation.
Thermo Fisher Scientific this week also introduced NUNC 384-Well Polypropylene Plates with an added feature that the company said improves the user’s ability to achieve a secure seal when using commercially-available heat seal tapes and instruments.
The new design features a raised rim around each well that promotes a robust, secure seal in all wells, enables plates to be re-sealed multiple times, and is compatible with adhesive seal tapes.
Midsci/Binder this week introduced its new CO2 incubator that the company said can culture cells without the risk of contamination.
The Binder C 150 CO2 incubator has standard hot-air sterilization at 180 °C and an interior that is condensation-free, even at high humidity levels. It is also equipped with a Fabry-Perot interferometer infrared measuring system without drift error.
The seamless, deep-drawn inner chamber now has 27 percent less surface area, and thus less potential surface for contamination, according to the manufacturer. In addition, the interior fittings of the incubator have been reduced to the absolute minimum, to optimize the equipment’s usable space-to-volume ratio.
Molecular Devices will be unveiling the AquaMax 2000 and AquaMax 4000 series of microplate washers at ScanLab 2007 in Stockholm, Sweden, September 24-26, and at Biotechnica 2007 in Hannover, Germany, October 9-October 11, the company announced this week.
The modular design of this new washer platform allows researchers to configure the system for their current microplate format and applications, and provides an affordable upgrade path when assay requirements change, the company said. The system's 96- and 384-well wash heads are user-interchangeable to extend the capabilities of the system on a single instrument platform.