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Altana, Definiens, Beckman, Immune Tolerance Network, Amaxa

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Altana to Install Definiens Imaging Software

Altana Pharma will adopt Definiens' biomedical image-analysis software, the companies said this week.

Neither of the Germany-based companies disclosed financial terms of the deal regarding Definiens' Cellenger software.


Beckman, Immune Tolerance Network Open Cell-based Assay Core Lab

Beckman Coulter and the Immune Tolerance Network have opened a core laboratory to develop, standardize, and automate cell-based tests for clinical trials at Beckman's facility in Miami, the company said this week.

Researchers from ITN, Beckman, and investigators from the US and Europe plan to develop and validate new cellular assays of T-cell responses for monitoring immune tolerance in clinical trials. "We believe that Beckman Coulter has a special expertise in these areas and look forward to working with the company in developing a number of these assays," said Hugh Auchincloss, chief operating officer of ITN, in a statement.

The Immune Tolerance Network, based at the University of California, San Francisco, is an international research collaboration with a dozen core facilities.


Amaxa to Optimize Nucleic Acid Technology Using ATCC Cell Lines

Amaxa said this week that it has signed a deal under which it will develop and optimize protocols for its nucleofector nucleic acid transfer technology using cell lines from the American Type Culture Collection.

"It is our goal to enable our customers to genetically manipulate the cell types they consider the best experimental model," Rainer Christine, CEO of Amaxa, said in a statement. "In looking for a partner, we needed a large collection of cell lines that came with reliable authentication. ATCC was the obvious choice."

Additional terms of the arrangement were not disclosed.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.