NEW YORK (GenomeWeb) – An international team led by investigators at Massachusetts General Hospital described mutations in a cadherin-coding gene, DCHS1, that are capable of causing a heart disease called mitral valve prolapse.

As they reported today in Nature, the researchers did targeted sequencing on four members of a family affected by non-syndromic mitral valve prolapse, focusing on a chromosome 11 region implicated in a previous study.

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