News on molecular diagnostics, pharmacogenomics tests for coronary artery disease, congenital heart defects, and more.
Using transcription data from cells and nuclei, the researchers uncovered heterogeneity within cardiac cells and mapped them to particular regions of the heart.
The University of Groningen-led team further uncovered variants associated with risk of dilated cardiomyopathy.
A spontaneous coronary condition that is overrepresented in young women had a polygenic risk score linked to lower-than-usual atherosclerosis-related heart disease risk.
The TAILOR-PCI trial did not meet its primary endpoint but did find that genetic testing led to a reduction in adverse events, though not as much as expected.
The AHA said genetic testing is useful in the management of several inherited diseases such as cardiomyopathies and familial hypercholesterolemia.
