News on molecular diagnostics, pharmacogenomics tests for coronary artery disease, congenital heart defects, and more.
Data from almost 19,500 individuals did not show clear ties between a heterozygous mutation in the HBB hemoglobin beta gene and ischemic stroke risk.
The prospective analysis suggests that the approach could help clinicians identify patients at risk of a stroke who could benefit from anticoagulant treatment.
Researchers saw clinically actionable heart disease mutations in fewer than 5 percent of sudden infant death syndrome cases interrogated by molecular autopsy.
Analyzing samples from Iceland and elsewhere, researchers uncovered one known and two new risk loci for aortic valve stenosis that are also associated with other heart risk pathways.
Using data for nearly 59,000 UK Biobank participants, researchers identified genes and pathways involved in heart rate variability, exercise response, and exercise recovery.
