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Cardiovascular Disease

News on molecular diagnostics, pharmacogenomics tests for coronary artery disease, congenital heart defects, and more.

Blood-Based 'Omics Signatures Reflect 'Biological' BMI, Metabolic Health

Features found in the blood offered a more refined look at obesity and related conditions, shifting more readily than body mass index in response to lifestyle changes.

Cardio Diagnostics Enters Private Financing Agreement for up to $11.2M

The firm intends to use the proceeds to accelerate the adoption of its PrecisionCHD and Epi+Gen CHD tests and to launch additional tests.

Polygenic Risk Score, AI Tool May Help Patients Reduce Inherited Heart Disease Risk, Study Suggests
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University of Cambridge researchers said at the American College of Cardiology annual meeting that they plan to make the PRS and AI tool publicly available through an online app.

Most Patients With Inherited Heart Conditions Not Getting Guideline-Backed Genetic Testing

Researchers analyzed electronic health and claims records to discover very low genetic testing rates among patients with five inherited cardiovascular conditions.

Earlier CYP2C19 Testing Linked With Lower Risk of Cardiovascular Events, Study Shows
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In multiple presentations, researchers at ACC/WCC's annual meeting explored the impact of genotyping cardiac patients within a week of starting dual anti-platelet therapy.

Feb 9, 2023

AGBT: cfDNA Methylation Profiling Shows Promise as Blood Biomarker for Congestive Heart Failure

Jan 25, 2023

Cardiac-Related Consequences of Alcohol Flushing Genetic Variant Reduced by Drug

Jan 17, 2023

Venous Thromboembolism Risk Rise Reported in Individuals With Extra Sex Chromosomes

Dec 7, 2022

Intermountain Builds Up Bioinformatics to Make HerediGene Sequencing Data Clinically Actionable
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Nov 29, 2022

Allelica, UAB to Study Clinical Value of Polygenic Risk Scores for Coronary Artery Disease

Oct 27, 2022

23andMe Gains FDA Clearance for Simvastatin Pharmacogenetic Report

Oct 27, 2022

Cardio Diagnostics Prepares for New Test Launches Following IPO
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Oct 25, 2022

Nest Genomics Building EHR-Integrated Clinical Decision Support for Genetics-Informed Care
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Oct 12, 2022

Singapore's VarNet Algorithm Seeks to Improve Somatic Variant Calling With Deep Learning
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Oct 4, 2022

Sequencing Data Helps Elucidate Blood Pressure Ties to Rare Sodium Channel Mutations

Sep 30, 2022

Stroke Risk Contributors, Treatment Targets Uncovered in Cross-Ancestry GWAS

Sep 28, 2022

MiRxes Launches Study for Pulmonary Hypertension Biomarkers in Asian Populations

Sep 23, 2022

Study Finds Metabolomic States Informing Common Disease Risk

Sep 15, 2022

Heart Disease Genes Flagged by Rare Variant Analysis of Spontaneous Coronary Artery Dissection

Sep 14, 2022

CardioVar Consortium Wins $8.2M From NHLBI to Map Heart Disease Variants, Functional Effects

Sep 8, 2022

Cardior Pharmaceuticals MicroRNA PCR Kit Receives CE Marking

Sep 6, 2022

Saudi Investment Fund Dammam Valley Takes Majority Stake in Arcensus

Sep 2, 2022

NIH-Developed Blood Test Shows Promise for Predicting Pulmonary Arterial Hypertension Severity
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Aug 30, 2022

UK's NICE to Assess Use of CYP2C19 Tests for Guiding Therapy Selection in Stroke Patients
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Aug 23, 2022

Sudden Cardiac Death Risk Informed by Genome-Wide Polygenic Score for Heart Disease

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The Scan

Nucleotide Base Detected on Near-Earth Asteroid

Among other intriguing compounds, researchers find the nucleotide uracil, a component of RNA sequences, in samples collected from the near-Earth asteroid Ryugu, as they report in Nature Communications.

Clinical Trial Participants, Investigators Point to Importance of Clinical Trial Results Reporting in Canadian Study

Public reporting on clinical trial results is crucial, according to qualitative interviews with clinical trial participants, investigators, and organizers from three provinces appearing in BMJ Open.

Old Order Amish Analysis Highlights Autozygosity, Potential Ties to Blood Measures

Researchers in BMC Genomics see larger and more frequent runs-of-homozygosity in Old Order Amish participants, though only regional autozygosity coincided with two blood-based measures.

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.