News on molecular diagnostics, pharmacogenomics tests for coronary artery disease, congenital heart defects, and more.
A two-stage, case-control genetic association study has implicated rare variants in the PTGIS gene in idiopathic pulmonary arterial hypertension susceptibility.
Although polygenic risk scores for coronary artery disease can slightly improve standard risk assessment tools, the predicted clinical impact remains small.
Understanding the genetic causes of hypercholesterolemia could provide prognostic information to help treat patients, the researchers said.
The Ottawa-based molecular diagnostics maker also plans to enter applied markets in the near term, and ultimately point-of-care infectious disease testing.
Nine of the genes analyzed had limited or disputed evidence linking them to long QT syndrome, suggesting they should not be included in genetic testing panels.
