Team Begins Defining Cancer Risk Patterns for Distinct BRCA1, BRCA2 Mutations | GenomeWeb

NEW YORK (GenomeWeb) – In a study appearing online today in the Journal of the American Medical Association, researchers began to tease apart the differences in breast and ovarian cancer risk for women carrying various BRCA1 and/or BRCA2 gene mutations.

The international team, which included members of the "Consortium of Investigators of Modifiers of BRCA" (CIMBA) group, considered documented disease patterns for tens of thousands of women with BRCA1 or BRCA2 mutations.

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This online seminar will discuss the application of circulating tumor DNA (ctDNA) sequencing to evaluate the emergence of resistance mutations during therapy.