Skip to main content
Premium Trial:

Request an Annual Quote

Swift Bio, Fluxion Develop Liquid Biopsy Workflow

NEW YORK (GenomeWeb) – Swift Biosciences and Fluxion Biosciences have teamed up to develop a clinical oncology research workflow designed to detect somatic mutations from patient blood samples.

The jointly developed workflow uses Fluxion's IsoFlux system for circulating tumor cell enrichment along with Swift's Accel-Amplicon technology.

IsoFlux enriches rare tumor cells circulating in the blood using a combination of epithelial and mesenchymal markers, and delivers them at high purity for molecular analysis.

Meantime, Swift's Accel-Amplicon 56G Oncology Panel combines target enrichment, library preparation, and sequencing on Illumina platforms to provide sensitive mutation detection across 56 cancer-related genes using very low starting DNA inputs from the IsoFlux System.

The workflow and associated products are for research use only, the companies noted.

The Scan

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.

Breast Cancer Risk Gene Candidates Found by Multi-Ancestry Low-Frequency Variant Analysis

Researchers narrowed in on new and known risk gene candidates with variant profiles for almost 83,500 individuals with breast cancer and 59,199 unaffected controls in Genome Medicine.

Health-Related Quality of Life Gets Boost After Microbiome-Based Treatment for Recurrent C. Diff

A secondary analysis of Phase 3 clinical trial data in JAMA Network Open suggests an investigational oral microbiome-based drug may lead to enhanced quality of life measures.

Study Follows Consequences of Early Confirmatory Trials for Accelerated Approval Indications

Time to traditional approval or withdrawal was shorter when confirmatory trials started prior to accelerated approval, though overall regulatory outcomes remained similar, a JAMA study finds.