NEW YORK (GenomeWeb) – Mutations in regulatory regions of the genome may play a larger role in cancer than previously thought, according to researchers from Stanford University.

The researchers analyzed whole-genome sequence data of 436 individuals spanning eight cancer subtypes from the Cancer Genome Atlas, as well as data from the Encyclopedia of DNA Elements (ENCODE) Project and other regulatory annotations, to identify point mutations in regulatory regions.

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In PNAS this week: host contributors to typhoid fever risk, effects of obesity-related variants near TMEM18, and more.

Sep
20
Sponsored by
Ion Torrent

This webinar will discuss how next-generation sequencing (NGS) can help clinical research labs and pathologists save time, money, and samples compared to single-analyte oncology research assays.

Sep
21
Sponsored by
Roche

This webinar will demonstrate a new approach that combines precise FFPE tumor isolation with extraction-free DNA/RNA library preparation to minimize material losses and reduce the amount of tissue input required for NGS analysis.

Sep
27
Sponsored by
Philips Genomics

This webinar will present an in-depth look at how Memorial Sloan Kettering Cancer Center has developed and implemented a next-generation sequencing panel for mutational tumor profiling of advanced cancer patients.