Stanford Study of Breast Cancer Reveals Heterogeneity of Early Lesions, Recurrent PIK3CA Mutations | GenomeWeb

NEW YORK (GenomeWeb) – Researchers at Stanford University studying the development of breast cancer in individuals have found that early lesions are genetically heterogeneous and that mutations in a well-known cancer gene, PIK3CA, induce cell growth but don't always lead to cancer.

The study, published online today in Genome Medicine, proposes the mutational analysis of pre-cancerous lesions in the clinic and raises questions about the utility of PIK3CA as a diagnostic marker of cancer.

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