NEW YORK (GenomeWeb) – Using a new statistical analysis approach, researchers have uncovered thousands of rare somatic variants associated with cancer.

Rather than using a gene-centric approach to tease out driver mutations from within cancer sequencing data, researchers from the University of Maryland used a model that examines protein domain families. In that way, they identified protein domains — which they called "oncodomains" — that were shared across different proteins that are frequently mutated within cancer samples.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.

Nov
02
Sponsored by
Qiagen

This webinar will discuss the benefits of using unique molecular indices to overcome some challenges associated with next-generation sequencing panels.

Dec
05
Sponsored by
Agilent Technologies

This webinar will discuss a molecular barcode-based error correction method that enables combined mutation detection and DNA copy number profiling through circulating tumor DNA sequencing.