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NEW YORK (GenomeWeb) – A team led by researchers at the Karolinska Institute in Sweden has analyzed the proteomic landscape of breast cancer tumors, finding similar subclasses as transcriptome-based analyses but also additional ones.

Breast tumors can be divvied into five subtypes — basal-like, normal-like, HER2, luminal A, and luminal B — based on their expression of 50 transcripts, known as the PAM50, but the researchers, led by the Karolinska Institute's Janne Lehtiö, noted that many patients are still misclassified.

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