NEW YORK (GenomeWeb) – Researchers from the University of Montreal have developed a proteogenomic approach to identify tumor-specific antigens for use in cancer immunotherapies.

Tumor-specific antigens (TSAs) help the immune system respond to cancer, and cancer immunotherapies may target them to boost that response. But according to Montreal's Claude Perreault and his colleagues, approaches for uncovering TSAs have been beset by false-positive findings or meager yield, and have focused on mutated TSAs rather than aberrantly expressed TSAs.

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In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.

Jan
30
Sponsored by
Loop Genomics

This webinar will provide a comparison of several next-generation sequencing (NGS) approaches — including short-read 16S, whole-genome sequencing (WGS), and synthetic long-read sequencing technology — for use in microbiome research studies.

Feb
21
Sponsored by
L7 Informatics

This webinar will provide a first-hand look at how Gradalis, a clinical-stage immunotherapy developer, is using an information management solution from L7 to streamline its research, clinical, and manufacturing operations.

Feb
26
Sponsored by
Advanced Cell Diagnostics

This webinar will demonstrate how a research team at the Firestone Institute for Respiratory Health at McMaster University developed a cellular and molecular phenotyping pipeline using archived samples of lung tissue derived from patients diagnosed with fibrotic interstitial lung disease.