NEW YORK (GenomeWeb) – Researchers led by a team at Yale University School of Medicine have found that two hereditary cancer syndromes result in the loss of a type of DNA repair that renders tumor cells vulnerable to poly(ADP)-ribose polymerase (PARP) inhibitors, suggesting a new treatment for patients with advanced disease.

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Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.