Multiple Myeloma Patients of African, European Ancestries Harbor Different Gene Mutations

NEW YORK (GenomeWeb) – Different genes tend to be mutated in multiple myeloma patients of African and European ancestry, a new study has found.

Researchers from the University of Southern California and elsewhere examined the genomes and transcriptomes of more than 700 multiple myeloma patients to determine whether there were molecular differences in disease by patient ancestry. Multiple myeloma occurs more frequently and is more likely to be fatal among African Americans than European Americans.