Skip to main content
Premium Trial:

Request an Annual Quote

Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study

NEW YORK — Lunaphore Technologies said on Thursday that it has partnered with the University of Bern to study tumor budding in colorectal cancer.

The partners will use Lunaphore's Comet immunostaining platform to study colorectal cancer tumor buds, which the company said are defined as a single tumor cell or a cluster of up to four cells that are lying at the invasive front of the primary tumor site and can be seen streaming through the stroma and entering vessels.

The platform, which combines a high-throughput stainer and a fluorescent microscope, will enable multiplexed immunostaining of tumor buds and the surrounding microenvironment in cancer tissue sections, according to Tolochenaz, Switzerland-based Lunaphore.

"We believe that [tumor buds] are a key component in the process of tumor dissemination and metastasis," Inti Zlobec, director of the translational research unit at the University of Bern's Institute of Pathology, said in a statement. "This project will be crucial to further our understanding of their biology and to extract novel prognostic factors from the tumor microenvironment."

The collaboration is being funded with a grant from the Swiss Innovation Agency.

In early 2020, Lunaphore raised about $2.1 million in Series C2 financing.

The Scan

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.

Neurological Outcomes Linked to Innate Immune Features After Cardiac Arrest

Researchers reporting in Med dig into immune features found a few hours after cardiac arrest that correspond with neurological outcomes.

Mouse Study Finds Circadian Rhythm-Related Gene Expression Changes Linked to Sleep Apnea

A paper in PLOS Biology reveals tissue-specific circadian rhythm and gene expression patterns in an intermittent hypoxia-based mouse model of obstructive sleep apnea.

Polygenic Risk Score to Predict Preeclampsia, Gestational Hypertension in Pregnant Women

Researchers in Nature Medicine provide new mechanistic insights into the development of hypertensive disorders of pregnancy, which may help develop therapeutics.