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NEW YORK (GenomeWeb) – Patients' human leukocyte antigen (HLA) genotypes influence how well they respond to immunotherapy, according to a new study.

HLA class I molecules bind peptides from intracellular proteins, including tumor proteins, and present them to CD8+ T cells that kill infected or cancerous cells. Immunotherapies that have been successful in treating some metastatic cancers rely on CD8+ T cells and HLA class I activity to work.

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Mar
11
Sponsored by
Foundation Medicine

In this session, the third in the Precision Oncology News Virtual Molecular Tumor Board Series, our expert panelists will review patient cases in which genomic profiling has identified gene fusions that may or may not serve as druggable targets.

Mar
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Sponsored by
IONPath

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Mar
23
Sponsored by
Roche

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Mar
24
Sponsored by
Mission Bio

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