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NEW YORK (GenomeWeb) – Members of the Children's Oncology Group have generated evidence supporting the notion that a five-gene expression signature can help predict survival patterns for pediatric rhabdomyosarcoma cases lacking a fusion between the PAX and FOXO1 genes.

Researchers from the US, Switzerland, and the UK set out to test the prognostic potential of the previously described signature in 57 children who appeared to fall in an intermediate risk group. Their findings are slated to appear today in Clinical Cancer Research.

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