Skip to main content
Premium Trial:

Request an Annual Quote

Exai Bio Raises $67.5M in Series A Round for Liquid Biopsy Early Cancer Detection Platform

NEW YORK Liquid biopsy test developer Exai Bio said Thursday that it has closed a $67.5 million Series A financing round to accelerate development of an RNA-based liquid biopsy platform for early cancer detection.

Life sciences and technology investors Section 32 and Casdin Capital led the financing round, with participation from Two Sigma Ventures.

San Francisco-based Exai Bio said its testing platform enables early diagnosis of cancer from blood samples to inform personalized treatments.

The platform uses artificial intelligence and machine learning algorithms to analyze cell-free RNA profiles, with a specific focus on orphan noncoding RNA — small RNA sequences not seen in normal tissue that are abundant in tumors.

Exai Bio holds an exclusive license for the development and commercialization of its testing platform from the University of California, San Francisco Innovation Ventures’ Office of Technology Management & Advancement.

The technology has been used in multiple studies, including the I-SPY 2 trial, conducted in collaboration with UCSF, which is designed to improve outcomes in individuals with high-risk breast cancer, Exai Bio said.

Hani Goodarzi, cofounder and scientific adviser for the firm, presented data from I-SPY 2 on Thursday at the San Antonio Breast Cancer Symposium in San Antonio, Texas.

"The data in the neoadjuvant breast cancer setting is significant, as early-stage breast cancer has been a difficult target for ctDNA-based liquid biopsy approaches," Goodarzi said in a statement.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.