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NEW YORK (GenomeWeb) – Two research teams have mapped out genes that cancer cells depend on for growth and survival.

Using genome-wide RNA interference screens, research teams from both the Broad Institute and Novartis knocked down thousands of genes in hundreds of cancer cell lines. By then examining which cells survived, the researchers could gauge whether cancer cells were dependent upon the silenced genes. The teams reported their results today in separate Cell papers.

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Jun
26
Sponsored by
Lexogen

This webinar will outline a study that combined genome-wide and classical molecular approaches to demonstrate that translation strongly affects mRNA stability in a codon-dependent manner, ultimately influencing mRNA and protein levels in higher organisms.

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23
Sponsored by
Qiagen

This webinar will discuss how the Molecular Pathology Laboratory at the University of Oklahoma (OUMP) is using a new quality improvement model to support molecular testing of oncology patients. 

Jul
30
Sponsored by
Mission Bio

This webinar will outline a project that performs large-scale and integrative single-cell genome and transcriptome profiling of pediatric acute lymphoblastic leukemia (ALL) cases at diagnosis, during drug treatment, and in case of relapse.