NEW YORK (GenomeWeb) – Scientists have used CRISPR/Cas9 to create a comprehensive genetic screen of the mouse genome. Using guide RNAs developed to knock out genes in the 2.6 billion base pair mouse genome, the scientists revealed new genes involved in tumor evolution and metastasis.

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Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.