Skip to main content
Premium Trial:

Request an Annual Quote

Biogazelle, Isis Pharmaceuticals Collaborate on Long Non-Coding RNA Technology

NEW YORK (GenomeWeb) – Biogazelle today announced a research collaboration with Isis Pharmaceuticals to identify and validate novel drug targets. 

The collaboration is aimed at treatments for colon, liver, and lung cancer. Isis will provide Biogazelle with access to its antisense platform for the large-scale validation of therapeutic long non-coding RNA targets from Biogazelle's target identification pipeline. 

Financial and other details of the deal were not disclosed. 

Antisense drugs are small DNA- or RNA-like compounds that degrade complementary RNA targets inside a cell. In recent years, antisense drugs have been developed to treat diseases by targeting disease-associated protein-coding mRNA targets, Biogazelle said. 

LncRNA represents a new class of RNAs that do not code for proteins, and evidence suggests they play an important role in cancer development and progression, the Ghent, Belgium-based company added. 

"This collaboration broadens the application of our technology to this promising new area and provides us with a knowledgeable partner that has the diagnostic expertise and experience to quickly advance from screening to target validation," C. Frank Bennett, senior vice president of research at Isis Pharmaceuticals, said in a statement. 

Founded in 2007 as a spinoff of Ghent University, Biogazelle leverages RNA sequencing, digital PCR, and its qbase+ software to provide gene expression analysis services.

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.