Auburn U, Gen9, Autodesk Collaborate on Synthetic Oncolytic Virus to Treat Cancer in Dogs | GenomeWeb

NEW YORK (GenomeWeb) – A collaboration between a veterinary oncologist, synthetic DNA manufacturer Gen9, and design software firm Autodesk claims to have created the largest synthetic viral genome to date, which will be used in clinical trials to treat cancer in dogs using oncolytic viruses.

The synthetic canine adenovirus Type 2 (CAV-2) genome measures between 32 and 33 kilobases, a record, based on a recent literature search, Gen9 VP of Research and Development Devin Leake told GenomeWeb. He noted that several synthetized bacterial genomes have been larger.

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The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.

The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.

Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.

In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.

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