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risk stratification

Protein Biomarkers May Predict Obese Patients at Risk of Liver Inflammation

Researchers profiled liver-secreted and blood plasma proteins and proposed a set of six plasma biomarkers for metabolic-associated steatohepatitis (MASH).

Germline Variant Effects on Cancer Proteomes Spelled Out in 'Precision Peptidomics' Study

Researchers analyzed multiomic data for 1,064 patients with 10 cancer types, identifying common and rare germline variants influencing protein expression and function.

Hackensack Meridien Health Launches Cancer Risk, Early Detection Program; Eyes Multi-Cancer Testing
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Patients will be offered germline genetic testing after an assessment that includes genetic, lifestyle, and other clinical risk factor analysis.

Machine Learning Approach Helps Identify New Rare Variants Linked to Heart Disease
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A computationally derived score captured the severity, progression, and underdiagnosis of coronary artery disease.

UK's NICE Expands Tumor Profiling Recommendations for Guiding Adjuvant Chemo in Early Breast Cancer

Previously, NICE recommended EndoPredict, Prosigna, and Oncotype DX for node-negative breast cancer only, but the new guidance includes lymph node-positive disease. 

Jan 26, 2024

Trial Failure Raises Questions About MRD Testing Utility, but Prognostic Evidence Remains Strong

Jan 17, 2024

Healthy Nevada Researchers Consider Impact of Low Genetic Breast Cancer Risk on Screening Guidelines
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Dec 11, 2023

Oncotype DX Shows Value in Interim Results From Two Radiation Trials at SABCS Meeting
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Nov 21, 2023

Innosign Aims to Improve Cancer Recurrence Risk Testing With Pathway Classifier Technology
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Oct 24, 2023

NCI Grants to Fund Myeloid Leukemia Research at Ohio State, NYU

Jul 25, 2023

ACMG Workgroup Addresses Cancer Risk Variability With CHEK2 Alterations in Practice Resource

Apr 28, 2023

Pacific Edge Ramps up Clinical Utility Studies, Commercial Efforts Behind Bladder Cancer Test
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Apr 26, 2023

Model Predicts Blood Cancer Progression Risk for Clonal Hematopoiesis Patients
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Apr 17, 2023

COPD Risk Loci Uncovered With GWAS, Machine Learning-Based Phenotyping

Jan 17, 2023

Inflammatory Gene Expression Score IDs High-Risk AML Patients
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May 20, 2022

Palmetto Finalizes Positive LCD for Prostate Cancer Risk Tests

Apr 5, 2022

Polygenic Transcriptome Risk Scores for COPD Show Improved Cross-Ancestry Portability

Feb 22, 2022

Arcensus Hopes DTC Testing Will Help Genome Sequencing Become First-Line Rare Disease Diagnostic
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Dec 10, 2021

Researchers ID Genomic Signature to Risk Stratify Patients With Precancerous Breast Lesions

Oct 27, 2021

Polygenic Risk Scores Edge Toward Clinic, Though Disease Prediction Utility Questions Linger
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Sep 28, 2021

Genetic Technologies, WashU Team up to Study Breast Cancer Risk in Woman of African Descent

Sep 16, 2021

Polygenic Risk Scores for Breast, Prostate Cancer Adaptable for Cross-Ancestry Use, Study Shows

Aug 27, 2021

Oncocyte Launches Prospective Registry to Drive DetermaRx Adoption, Improve Coverage
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Jul 28, 2021

Sequencing Firm Phosphorus Tests Limits of Comprehensive Consumer Genomics With GeneCompass
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Jul 22, 2021

Volpara Adding Invitae Genetic Test Ordering to Breast Risk Software Platform