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Papers of Note: Oct 7, 2010


RNAi- and microRNA-Related Papers Published September 2010

Notably, the findings also indicate that the toxic effects may not be solely the result of interference with the microRNA pathway, but also with other small regulatory RNAs that have yet to be identified.

Papers of Note: Sep 2, 2010


RNAi- and microRNA-Related Papers Published August 2010

Papers of Note: Aug 12, 2010


RNAi- and microRNA-Related Papers Published July 2010

The first study found that Ago2-deficient mice self-administered cocaine less than their control counterparts, while the second linked expression of one specific microRNA with the motivational properties of the drug.

Galas and colleagues last week published a report describing the triggering of miRNA export following serum deprivation in culture, as well as the discovery of a number of proteins that may be involved in the process.

The findings not only show that miRNAs are "a novel class of signaling molecules that play an important role in mediating cell-to-cell and organ-to-organ communication," but also demonstrate that the small, non-coding RNA are part of "a highly regulated complex network under various physiological and pathophysiological conditions," according to a study author.

The new research demonstrates that agRNAs that target non-coding RNAs corresponding to regions beyond the 3' termini of genes can also silence or activate genes in a sequence-specific manner.

Papers of Note: Jul 8, 2010


RNAi- and microRNA-Related Papers Published June 2010

Papers of Note: Jun 3, 2010


RNAi- and microRNA-Related Papers Published May 2010


Researchers have sequenced the genome of the depth-dwelling giant squid.

Prosecutors have charged a former Drexel University professor with theft for allegedly spending federal grant money on adult entertainment and other unrelated expenses, according to the Philadelphia Inquirer.


Chris Collins, a former US representative, has been sentenced to more than two years in prison in an insider trading case involving an Australian biotechnology firm, the New York Times reports.

In PNAS this week: Trypanosoma brucei transcripts, estimate of people at risk of inherited retinal disease, and more.