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RNAi- and microRNA-Related Papers Published September 2011

RNAi- and microRNA-Related Papers Published August 2011

Scott Hammond
Associate professor, cell and developmental biology, University of North Carolina, Chapel Hill

Mice treated with a miR-33 antagonist displayed increased HDL-C, enhanced reverse cholesterol transport to the plasma, liver, and feces, and reductions in plaque size and lipid content.

Papers of Note: Jun 2, 2011


RNAi- and microRNA-Related Papers Published May 2011

According to a paper published in Nature, miR-148a was found to regulate the expression of HLA-C, which plays a key role in immunity, with a variant having been associated with HIV load and progression to AIDS.

Ambati and colleagues reported this month that Dicer1 depletion triggered the degeneration of retinal pigmented epithelium cells, a hallmark of the severest form of dry AMD, in human cells and mouse models.

Papers of Note: Feb 3, 2011


RNAi- and microRNA-Related Papers Published January 2011

Papers of Note: Dec 9, 2010


RNAi- and microRNA-Related Papers Published November 2010

The siRNAs inhibited tumor necrosis factor-alpha, a pro-inflammatory cytokine implicated in a variety of inflammatory diseases, in the animals' colons and protected against ulcerative colitis, according to the paper.


The Washington Post reports that a Russian Academy of Sciences commission has led to the retraction of hundreds of scientific papers.

The Los Angeles Times' Daily Pilot reports the chief executive of Vantari Genetics has pleaded guilty in a kickback scheme.

News 4 Jax reports that a Florida bill to prevent life and long-term care insurers from using genetic information in their coverage decisions has easily passed one committee.

In Science this week: potentially pathogenic mutations found in hematopoietic stem cells from young healthy donors, and more.