peer-reviewed publication MIT Researchers Devise Oligo Barcode-Based 'File System' for DNA Data Storage Premium The researchers have applied for a patent on their technology and have formed a startup, Cache DNA, to develop a low-cost platform for DNA storage and retrieval. Global Subway Metagenomics Study Reveals Cities' Microbial Fingerprints The study found more than 10,000 viruses and hundreds of bacteria not present in any reference database, along with other novel genomic features. New Algorithms Enable Direct Nanopore-Based Detection of Additional RNA Modifications Premium The method was used to analyze two epigenetic modification types that were previously undetectable with Oxford Nanopore sequencing. Long-Read Genome Assemblies Have 'Blind Spots' for Structural Variant Detection Premium Researchers comparing structural variant detection using short- and long-read technologies said assembly-based methods can provide added value, despite missing certain CNVs. New Method Provides NGS-Based Readout of Glycan Levels in Single Cells Premium SUGAR-seq, a single-cell method developed by researchers in Australia, is a first step towards analyzing differences in glycosylation in various cell types. Feb 1, 2021 Expansion Sequencing Improves on Church Lab's In Situ Transcriptomics Method Premium Jan 11, 2021 Broad Institute, MIT Researchers Probe Genome Structure With New In Situ DNA Sequencing Method Premium Dec 8, 2020 New Methods Enable Phased Human Genome Assemblies Without Parental Data Premium Nov 17, 2020 New NGS-Based Tissue Analysis Method Offers Spatial Detail on Transcriptome, Proteins Premium Sep 9, 2020 Adaptive Biotechnologies, Takara Bio T Cell Receptor Sequencing Methods Rank High in Benchmarking Study Premium Sep 9, 2020 Machine Learning Tool Enables Analysis of Complex, Polygenic Phenotypes With Epistastic Interactions Premium Aug 31, 2020 New Methods Boost Scale of Single-Cell Gene Expression Dynamics Studies Premium Jul 30, 2020 Double-Barcoded Single-Cell Library Prep Solves Index-Hopping Issues, Lowers Sequencing Costs Premium Jun 15, 2020 Genome In a Bottle Consortium Releases Structural Variant Calling Benchmark Data Premium Jun 11, 2020 Avida Biomed Developing Hybridization-Based Methylation Sequencing Panels for Cancer Dx Premium Jun 2, 2020 10x Genomics, Collaborators Develop Targeted Single-Cell Gene Expression Methods Premium Apr 27, 2020 Rockefeller University, Cerevance Pursue Pooled Nuclei Sequencing to Target Brain Cell Types Premium Apr 23, 2020 Harvard Spinout 1CellBio Seeks Ideas for Applications of Targeted Single-Cell Tech Premium Mar 26, 2020 GigaMune Hopes to Offer TCR Screens to Pharmas While Scrambling to Keep Expression Libraries Alive Premium Mar 5, 2020 New Sepsis Test Uses Nanopore Sequencing to Detect Pathogens From Cell-Free DNA Premium Feb 10, 2020 Nanopore Sequencing-Based Mapping Methods Reveal Open Chromatin, Methylation Patterns Premium Jan 13, 2020 Integrated Single-Cell RNA-Seq, Array Spatial Transcriptomics Analysis Puts Cells Into Context Dec 5, 2019 High-Throughput Single-Cell Transcriptomics Assay Facilitates Compound Screens Premium Dec 3, 2019 SciLifeLab Researchers Develop Multiplexed Library Prep Method for FFPE Samples Premium Aug 15, 2019 HiFiBio Bets on Single-Cell Methods to Boost Drug Discovery Premium Load More Breaking News In Brief This Week: Illumina, Personalis, Proteomedix, and More Ancient DNA Details Population Dynamics Within Andean Tiwanaku Civilization Genomic Data Spanning 2K Years Gives Glimpse of Etruscan Origins, Population Changes People in the News: New Appointments at Hologic, Akoya Biosciences, Caris Life Sciences, More At NSGC, Genetic Counselors Address Race-Based Medicine, Ways to Change New Products Posted to GenomeWeb: Becton Dickinson, Cosmos-ID, OncoDNA, More The Scan US Booster Eligibility Decision The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions. Arizona Bill Before Judge The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction. Additional Genes Wales is rolling out new genetic testing service for cancer patients, according to BBC News. Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.