peer-reviewed publication MIT Researchers Devise Oligo Barcode-Based 'File System' for DNA Data Storage Premium The researchers have applied for a patent on their technology and have formed a startup, Cache DNA, to develop a low-cost platform for DNA storage and retrieval. Global Subway Metagenomics Study Reveals Cities' Microbial Fingerprints The study found more than 10,000 viruses and hundreds of bacteria not present in any reference database, along with other novel genomic features. New Algorithms Enable Direct Nanopore-Based Detection of Additional RNA Modifications Premium The method was used to analyze two epigenetic modification types that were previously undetectable with Oxford Nanopore sequencing. Long-Read Genome Assemblies Have 'Blind Spots' for Structural Variant Detection Premium Researchers comparing structural variant detection using short- and long-read technologies said assembly-based methods can provide added value, despite missing certain CNVs. New Method Provides NGS-Based Readout of Glycan Levels in Single Cells Premium SUGAR-seq, a single-cell method developed by researchers in Australia, is a first step towards analyzing differences in glycosylation in various cell types. Feb 1, 2021 Expansion Sequencing Improves on Church Lab's In Situ Transcriptomics Method Premium Jan 11, 2021 Broad Institute, MIT Researchers Probe Genome Structure With New In Situ DNA Sequencing Method Premium Dec 8, 2020 New Methods Enable Phased Human Genome Assemblies Without Parental Data Premium Nov 17, 2020 New NGS-Based Tissue Analysis Method Offers Spatial Detail on Transcriptome, Proteins Premium Sep 9, 2020 Adaptive Biotechnologies, Takara Bio T Cell Receptor Sequencing Methods Rank High in Benchmarking Study Premium Sep 9, 2020 Machine Learning Tool Enables Analysis of Complex, Polygenic Phenotypes With Epistastic Interactions Premium Aug 31, 2020 New Methods Boost Scale of Single-Cell Gene Expression Dynamics Studies Premium Jul 30, 2020 Double-Barcoded Single-Cell Library Prep Solves Index-Hopping Issues, Lowers Sequencing Costs Premium Jun 15, 2020 Genome In a Bottle Consortium Releases Structural Variant Calling Benchmark Data Premium Jun 11, 2020 Avida Biomed Developing Hybridization-Based Methylation Sequencing Panels for Cancer Dx Premium Jun 2, 2020 10x Genomics, Collaborators Develop Targeted Single-Cell Gene Expression Methods Premium Apr 27, 2020 Rockefeller University, Cerevance Pursue Pooled Nuclei Sequencing to Target Brain Cell Types Premium Apr 23, 2020 Harvard Spinout 1CellBio Seeks Ideas for Applications of Targeted Single-Cell Tech Premium Mar 26, 2020 GigaMune Hopes to Offer TCR Screens to Pharmas While Scrambling to Keep Expression Libraries Alive Premium Mar 5, 2020 New Sepsis Test Uses Nanopore Sequencing to Detect Pathogens From Cell-Free DNA Premium Feb 10, 2020 Nanopore Sequencing-Based Mapping Methods Reveal Open Chromatin, Methylation Patterns Premium Jan 13, 2020 Integrated Single-Cell RNA-Seq, Array Spatial Transcriptomics Analysis Puts Cells Into Context Dec 5, 2019 High-Throughput Single-Cell Transcriptomics Assay Facilitates Compound Screens Premium Dec 3, 2019 SciLifeLab Researchers Develop Multiplexed Library Prep Method for FFPE Samples Premium Aug 15, 2019 HiFiBio Bets on Single-Cell Methods to Boost Drug Discovery Premium Load More Breaking News Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets LSU Health Sciences Center Wins $2.4M to Lead SARS-CoV-2 Variant Sequencing Program NanoString Technologies, Parker Institute for Cancer Immunotherapy Partner on Cell Therapy Project BGI Americas Collaborating With Champions Oncology on Proteomic Cancer Research Personal Genome Diagnostics Inks Cancer Genomic Profiling Deal with Duke University Health System The Scan Missed Early Cases A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports. Limited Journal Editor Diversity A survey finds low diversity among scientific and medical journal editors, according to The Scientist. How Much of a Threat? Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned. PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.