peer-reviewed publication
New studies suggest many methods that map NGS reads to a reference can be improved using a graph-based reference genome rather than a linear one.
New Enzymatic Approach Enables Transcriptome-Wide N6-Methyladenosine Profiling, Quantification
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The method, dubbed eTAM-seq, offers scientists a new way to study m6A modifications in mRNA at a high resolution while lowering the sample input requirement.
Image-seq deploys in vivo or in situ imaging to isolate cells from specific tissue locations for single-cell sequencing.
Using CRISPR-CATCH, researchers can enrich and study megabase-sized ecDNA from human cancer cells, gaining insights into their heterogeneity and epigenome.
SMS-seq combines structural probing with direct RNA nanopore sequencing, offering researchers a new way to study RNA structure at the single-molecule level.
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