A Johns Hopkins team reported its finding in JAMA Cardiology, backed by SNP array data from 21,870 participants culled from several large cardiovascular studies.
Scientists reported this week for the first time a Danish reference genome based on the de novo assembly of 150 genomes from 50 family trios.
September's Bioinformatics Papers of Note
Bernstein BE, Birney E, et al.An integrated encyclopedia of DNA elements in the human genome.Nature. 2012 Sep 6;489(7414):57-74.
Next-generation sequencing identifies novel microRNAs in peripheral blood of lung cancer patients.
Keller A, Backes C, Leidinger P, et al.Mol Biosyst. 2011 Oct 25. [Epub ahead of print]
First survey of the wheat chromosome 5A composition through a next generation sequencing approach.
Vitulo N, Albiero A, Forcato C, et al.PLoS One. 2011;6(10):e26421.
Bioinformatics Tool-Related Papers of Note, October 2011
Temporal dissection of tumorigenesis in primary cancers.
Durinck S, Ho C, Wang NJ, Liao W, et al.Cancer Discov. 2011 Jul 1;1(2):137-143.
Analysis of 16S rRNA amplicon sequencing options on the Roche/454 next-generation Titanium sequencing platform.
Tamaki H, Wright CL, Li X, Lin Q, et al.PLoS One. 2011;6(9):e25263.
Bioinformatics Tool-Related Papers of Note, June 2011
Frequent pathway mutations of splicing machinery in myelodysplasia.
Yoshida K, Sanada M, Shiraishi Y, et al.Nature. 2011 Sep 11. [Epub ahead of print]
The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.
Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.
In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.
Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.