The firm hopes the effort, recently described in the journal Oncotarget, will spur adoption of its testing services by oncologists, particularly in Europe, where it is determined to become a market leader.
The effort, which relied on Oxford BioDynamics' EpiSwitch platform, resulted in an assay that researchers believe could be developed into a test to guide therapy selection for patients.
Given the high yield of miRNA markers they were able to isolate, the researchers believe the approach could be commercialized for routine cancer testing.
A Johns Hopkins team reported its finding in JAMA Cardiology, backed by SNP array data from 21,870 participants culled from several large cardiovascular studies.
Scientists reported this week for the first time a Danish reference genome based on the de novo assembly of 150 genomes from 50 family trios.
September's Bioinformatics Papers of Note
Bernstein BE, Birney E, et al.An integrated encyclopedia of DNA elements in the human genome.Nature. 2012 Sep 6;489(7414):57-74.
Next-generation sequencing identifies novel microRNAs in peripheral blood of lung cancer patients.
Keller A, Backes C, Leidinger P, et al.Mol Biosyst. 2011 Oct 25. [Epub ahead of print]
First survey of the wheat chromosome 5A composition through a next generation sequencing approach.
Vitulo N, Albiero A, Forcato C, et al.PLoS One. 2011;6(10):e26421.
Bioinformatics Tool-Related Papers of Note, October 2011
Temporal dissection of tumorigenesis in primary cancers.
Durinck S, Ho C, Wang NJ, Liao W, et al.Cancer Discov. 2011 Jul 1;1(2):137-143.
Researchers have sequenced the northern white rhinoceros to gauge whether it could be brought back from the edge of extinction, the New York Times reports.
Bavaria expands its forensic genetic analyses to include DNA phenotyping, raising discrimination concerns.
Tufts University researchers found a role for miRNA in transmitting stress between generations, the Economist reports.
In Science this week: gut microbiome influences liver cancer growth, spread; and more.