papers of note Bioinformatics Method Could Improve Detection of Off-Target CRISPR Activity Premium Israeli researchers have developed CRISPector, which separates signal from noise better than earlier quality-control tools, a new paper shows. GWAS-Methylation Integration Could Help Identify Drug Repurposing Candidates for MS Premium In research presented at the AMIA Informatics Summit, University of Texas bioinformaticians tried a new algorithm to include epigenetic factors in predicting disease progression. UK Researchers Publish Data on qPCR-Based Early-Stage Lyme Disease Test Premium The test relies on using quantitative PCR to target genes encoded by prophages — viruses present in Lyme-causing bacteria, which can be easier to detect than the bacteria itself. Allelica Wants Polygenic Risk Scores to Become Routine in Heart Disease Care Premium The startup has developed software to automate polygenic risk score generation for hospitals and labs using microarray or sequencing data. Genomics Plc Looks to Grow 'Genomic Prevention' With Polygenic Risk Scores Premium In two recent papers, the UK startup demonstrated the integration of polygenic risk scoring into primary care screening and workflows. Mar 12, 2021 Harvard, Nvidia Team Develops Deep Learning Approach to Improve ATAC-Seq Quality Premium Dec 17, 2020 Danish Researchers to Integrate Genomic Data With New Disease Trajectory Browser Premium Dec 11, 2020 Cold Spring Harbor Lab Develops iPhone App for Mobile Sequencing Analysis Premium Nov 25, 2020 Recurrent SARS-CoV-2 Virus Mutations Do Not Increase Transmissibility, Study Finds Nov 4, 2020 Singapore's MiRxes Sets Out to Sell Gastric Cancer Test Across Asia Premium Oct 12, 2020 MD Anderson's DrBioRight Automates Omics Analytics With Natural-Language Technology Premium Sep 10, 2020 Researchers Encourage Forensics Labs to Adopt New Genomic Technologies for Relationship Testing Premium Sep 9, 2020 Machine Learning Tool Enables Analysis of Complex, Polygenic Phenotypes With Epistastic Interactions Premium Sep 2, 2020 Mount Sinai Bioinformaticians Identify Drug Candidates to Prevent SARS-CoV-2 Replication Premium Jun 24, 2020 Genetic Study Explains Link Between Osteoporosis Drug, Cardiovascular Risk Jun 15, 2020 Homomorphic Encryption Might Hold Key to Fast, Large-Scale GWAS Premium Jun 11, 2020 Sync for Genes Demonstrates Potential of Sharing Discrete Clinical Genomics Data Premium May 28, 2020 Mendelian Disease Diagnosis Gets Boost From Automated Software That Scans Full-Text Articles Premium Apr 14, 2020 New Studies Compare, Set Benchmarks for Single-Cell RNA Sequencing Methods Premium Dec 4, 2019 UK Researchers Implement Diagnostics.ai System to Improve Infectious Disease Testing Premium Dec 2, 2019 Columbia Study Finds Low Patient Engagement With Basic Genomic Education Videos Premium Sep 27, 2019 Study Investigates Trust in Genomic Data Sharing Initiatives to Inform Future Efforts Premium Aug 20, 2019 Stanford Team Uses Imputation Approach to Uncover Thousands of New Microbiome Proteins Premium Jun 14, 2019 Genes for Good Project Seeks Funding, Collaborations to Advance Use of Genetic Database Premium May 8, 2019 Almac Assay's Ability to Stratify Esophageal Cancer Patients Demonstrated by UK Researchers Premium Load More Breaking News Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy Space Radiation Shows Limited Effects on Mammalian Sperm DNA, Fertility Bluestar Genomics Sues Former Consultant, Ludwig Institute for Cancer Research Over IP Ownership New Products Posted to GenomeWeb: 10x Genomics, Swift Biosciences, Agilent Technologies, More In Brief This Week: Quantum-Si, TGen, Yale, and More People in the News: New Appointments at Invitae, PGDx, Oxford Nanopore, PacBio, More The Scan Fertility Fraud Found Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today. Ties Between Vigorous Exercise, ALS in Genetically At-Risk People Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports. Test Warning The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK. Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.