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The cost-cutting moves, which are expected to reduce Rosetta's annual operating costs by $4 million, come less than a month after the Israeli firm unveiled two new microRNA-based tests it has under development and said that it would be establishing its own sales force to market them and certain other of its next-generation products.

The firm hopes to cut its monthly burn rate 32 percent as it pushes forward with plans to launch second-generation miRview tests.

The emergence of new RNAi chemistries and technologies in recent years, and big pharma's growing interest in building up its own capabilities, suggest that Alnylam's status as the go-to partner in the field may be waning.

The firm will cut another 14 positions, on top of the previously announced 40 jobs, as it aims to reduce its operating costs.

A streamlining of its Life Sciences and Clinical Labs operations is expected to result in a reduction of annualized operating expenditures of $4 million.

The Canadian diagnostics firm aims to trim C$2 million in costs in 2011.

The firm expects to incur approximately $667,000 in restructuring costs.

The firm is pressing ahead with its plans to focus on the molecular diagnostics market. Part of its restructuring includes the departure of J. William Efcavitch as chief technology officer.

The firm reported that it had not received any revenues in the quarter tied to system sales. It had announced separately yesterday that it will reposition its focus on the molecular diagnostics industry.

Life Technologies will consolidate operations currently carried out in Camarillo, Calif., at its site in Maryland. The firm also will lay off an undetermined number of employees.

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Nature News reports that recent proposed changes to the US National Science Foundation have raised concerns about a shift away from the agency's focus on basic research.

Noel Rose, the "father of autoimmunity," has died at 92, the Washington Post reports.

According to CNN, Legionella was discovered in buildings leased by the Centers for Disease Control and Prevention as they reopened following coronavirus pandemic-related closures.

In PLOS this week: genetic analysis of malaria parasite populations in Southeast Asia, genomic surveillance of yellow fever virus in São Paulo, and more.