The firm's CEO Ramji Srinivasan said the layoffs would help focus the company on developing relationships with clinicians and medical providers.
In November, the company said it was selling off its biomedical commercialization and marketing services business in order to focus on its diagnostic offerings.
The company has scaled back its headcount from a peak of 115 employees to about 100 staff members, primarily on the commercial side.
Johnson & Johnson announced that it would be cutting about 3,000 jobs from its medical devices section.
The company said it earned approximately $128 million in revenue in 2015, and accessioned 42,000 total commercial diagnostic test samples.
Dragged down by sinking sales and test volumes at IDL, GeneNews looks to restructure its business.
The company plans to lay off 145 employees at its Mountain View headquarters, as well as 15 in San Jose, 13 in Sunnyvale, and six in San Francisco.
PDI said that the workforce reduction would save $400,000 in December, and shave $1.9 million off of its annual operating costs going forward.
In a regulatory document, the company said the layoffs resulted from a restructuring plan to "emphasize growth initiatives."
The majority of the charges were taken in the Life Sciences Solutions segment, "principally for severance obligations" to former employees and executives of Life Tech.
In Nature this week: genetic history of HIV in the US, and more.
There are a few projects aimed at addressing the lack of diversity in genomic research, Technology Review reports.
A national assessment shows that US students lag in the sciences, but suggests that achievement gaps are narrowing.
Harvard's George Church discusses HGP-write with the Journal of the American Medical Association.