guidelines

As the National Guideline Clearinghouse goes dark, the ECRI Institute says it will pick up the slack.

The updated recommendations discuss testing for DNA repair gene mutations, MSI-H, and dMMR, as well as germline testing and counseling.

The guidelines are the first to attempt to specify which drugs are appropriate to test for routinely, guideline authors say.

With only one test FDA-approved for primary hrHPV screening, groups express concern about feasibility of moving away from co-testing

The changes include recommendations for first line immunotherapy in patients with high PD-L1 expression, and clarification on use of targeted therapies.

Agendia said that the guidelines reflect MammaPrint's rank as the only multigene test to receive level 1A status, based on prospective, randomized data from the MINDACT clinical trial.

Call for Guidance

Harvard researchers call for a discussion and development of guidelines for 'embryoid' research, NPR reports.

The German Association of Gynecological Oncology included the breast cancer diagnostic in its annual update for cancer clinicians.

The recommendations were developed by a working group of the AMP Clinical Practice Committee that included representatives from ACMG, ASCO, and CAP.

The Clinical Pharmacogenetics Implementation Consortium hopes that the terms will be widely adopted by labs and help advance adoption of PGx test results across systems. 

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Cancer researcher Alan Rabson has died at 92, the New York Times reports.

As the National Guideline Clearinghouse goes dark, the ECRI Institute says it will pick up the slack.

In Genome Research this week: sequencing method examines proteins parasite uses to evade immune system, L1 insertions in cancer, and more.

The Atlantic reports on private Facebook support groups for people who receive unexpected parentage results from direct-to-consumer genetic tests.