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The BATTLE trial was the first prospective, adaptively randomized study in pretreated non-small cell lung cancer patients that mandated tumor profiling with “real time” biopsies. The 255 patients in the trial were adaptively randomized to four arms — erlotinib, vandetanib, erlotinib plus bexarotene, or sorafenib — based on their biomarker profiles.

The deal will provide "biopharmaceutical firms with a better understanding of modes of action of a variety of therapeutics and the role of biomarkers in the oncology drug development process."

The firm expects to complete the clinical trials this summer and then submit an application with FDA.

In the first study, four AIDS patients with lymphoma received treatment and are doing well, with no signs of treatment-related adverse effects.

The move marks the company's foray into the ranks of clinical-stage drug developers and its first steps toward becoming a therapeutics marketer.

The firm's shares jumped in early trade after a study published online on the American Journal of Obstetrics and Gynecology website showed the firm's T21 test demonstrated 100 percent sensitivity and 99.7 percent specificity.

The new FDA rule will require consent forms for medical device and drug trials to explain that data will be made public through an NIH website.

NCI intends to consolidate the nine groups that currently conduct trials in adult cancer patients into four state-of-the-art entities that will design and perform improved clinical trials of cancer therapies.

The company's vice president of corporate development said that Marina is "committed" to signing two partnerships before year end, but indicated that it may miss this goal if the terms of the deals aren't right.

The Phase I study is being conducted in the US and Israel with two patient subgroups — stratum I, which includes patients with chronic nerve atrophy and began dosing in March; and stratum II, which is enrolling patients with recent onset of NAION.

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The founder of MeTooSTEM, BethAnn McLaughlin, created a Twitter account purported to be that of an LGBTQ Native American professor at Arizona State University, the New York Times writes.

Novavax reports its candidate SARS-CoV-2 vaccine leads to immune responses, according to the Sydney Morning Herald.

Gene length is associated with lifespan in a comparative genomics study appearing in the Proceedings of the National Academy of Sciences that draws on the whale shark genome.

In Nucleic Acids Research this week: effort to annotate the rat transcriptome, web-based resource to characterize marine microbes, and more.