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The firms have begun a validation sudy of the Down syndrome test, which runs on Illumina’s HiSeq platform.

Efforts spearheaded by Sage Bionetworks and Genetic Alliance hope to encourage drug developers to share precompetitive genomic data from the comparator arms of drug trials and to give study participants more control over their own data generated in clinical investigations.

The companies' first project will be a renal cancer clinical trial for an undisclosed Quintiles client. The partners aim to identify genetic markers that are predictive of adverse events and efficacy.

Alnylam also released its first-quarter financial results, reporting higher losses and lower revenues.

However, the company confirmed that it is no longer commercializing its test, the Enigma ML Influenza A/B detection assay, in partnership with GlaxoSmithKline as was previously reported.

Enigma's testing platform combines fully automated sample extraction with real-time PCR amplification and detection and is designed to achieve results in less than one hour.

The BATTLE trial was the first prospective, adaptively randomized study in pretreated non-small cell lung cancer patients that mandated tumor profiling with “real time” biopsies. The 255 patients in the trial were adaptively randomized to four arms — erlotinib, vandetanib, erlotinib plus bexarotene, or sorafenib — based on their biomarker profiles.

The deal will provide "biopharmaceutical firms with a better understanding of modes of action of a variety of therapeutics and the role of biomarkers in the oncology drug development process."

The firm expects to complete the clinical trials this summer and then submit an application with FDA.

In the first study, four AIDS patients with lymphoma received treatment and are doing well, with no signs of treatment-related adverse effects.

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A federal judge has ruled that drug companies, device manufacturers, and universities need to provide missing clinical data from hundreds of trials to a federal website, ScienceInsider reports.

A genetic analysis suggests red pandas might actually belong to two different species, New Scientist reports.

NPR reports that the US Centers for Disease Control and Prevention has fixed the problem with some of its SARS-CoV-2 testing kits.

In Nature this week: epigenetic factors that prevent healthy aging and more.