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clinical trial

Cancer Trial Halted

After three deaths, Juno Therapeutics' trial of a chimeric antigen receptor T-cell treatment has been halted.

According to Myriad, the NOVA study shows that myChoice HRD can double the number of ovarian cancer patients who will respond to niraparib compared to other tests.

Promising Trial

A trial by Tesaro indicates that its PARP inhibitor can limit ovarian cancer growth in patients with and without BRCA mutations.

The study involved the largest cohort to date, but uncertainty around less-studied, moderate-risk genes remains, experts said at ASCO's annual meeting.

Researchers presented data suggesting that pharma companies are using basket studies to identify molecularly defined patient subsets who might benefit from their drugs.

For Safety

French officials release a report and move to strength safety measures for clinical trials, ScienceInsider reports.

Decades in the Making

A team describes its idea for a clinical trial data-sharing database, called Vivli, ScienceInsider reports.

The firm will look for metabolic profiles that could help diagnose asphyxia in human newborns, signatures that were derived from animal studies.

Protocols, Please

The Annals of Internal Medicine is requiring authors to publish their clinical trial protocols, according to Retraction Watch.

The company is working with DKFZ to evaluate its NuQ test, which can identify chromosome fragments circulating in blood and analyze them for epigenetic modifications.

Pages

The Washington Post writes that the approval in the US of a SARS-CoV-2 vaccine will be up to Peter Marks, a career official at the Food and Drug Administration.

According to ScienceInsider, the US National Academies of Science, Engineering, and Medicine is planning a study of racism in academic research.

NPR reports the US loan to Eastman Kodak to boost domestic pharmaceutical production is on pause following insider trading allegations.

In Cell this week: blood immune cell changes in COVID-19 patients and spatial transcriptomics in Alzheimer's disease.