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clinical trial

Researchers at the Hartwig Medical Foundation have launched a clinical trial that seeks to match tumor biomarkers with experimental and off-label drugs.

The lead investigators said that Foundation Medicine's NGS test will enable the beginning of targeted treatment within seven days of diagnosis. 

Trial Changes

NIH Director Francis Collins describes changes to improve clinical trials in JAMA this week.

Non-randomized studies have downsides, but researchers say they are a way to gather incremental evidence on precision oncology approaches without denying patients access.

The app lets physicians use their mobile phones to access clinical trial matching capabilities from the broader GenoSpace portfolio.

The company has launched a beta version of its clinical trial matching service, and is helping patients learn about precision medicine and find others with similar tumor profiles. 

Avoid These

Halloran Consulting's Laurie Halloran lists at Stat News the mistakes she sees startup companies make when pursuing a clinical trial.

Start It Themselves

Parents raise more than $1.8 million to start a clinical trial to help their daughter with Sanfilippo syndrome, Today reports.

Insider Info

A clinical trial PI faces insider-trading charges, according to Pharmalot's Ed Silverman.

A pair of Harvard Medical School researchers finds that pediatric clinical trials are often stopped early and sometimes never published.

Pages

The US Department of Justice has proposed a rule change to enable DNA to be collected from migrants, the Associated Press reports.

Bernard Fisher, a surgeon who changed how breast cancer is treated, has died at 101, the New York Times reports.

Washington Post columnist writes that she is skeptical about DNA-based diets.

In PNAS this week: recurrent inactivation of DEPDC5 in gastrointestinal stromal tumors, taxonomic reliability of GenBank sequences, and more.