NEW YORK (GenomeWeb) – Biodesix said today it has increased the size of its offering of Series G preferred shares in a follow-on sale, and has simultaneously entered a debt refinancing agreement with Innovatus Capital Partners for a $23 million term loan.

The company said it plans to use the additional capital to fund development of blood-based tests for guiding use of cancer immunotherapies, as well as to further the commercialization of its VeriStrat and GeneStrat lung cancer tests.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.