NEW YORK (GenomeWeb) – Strand Life Sciences is aiming to position its 152-gene cancer sequencing test for solid tumors as a tool that can be used early on in a patient's disease in order to inform first-line therapy.

The company launched a 48-gene version of the StrandAdvantage test in the US in April, but has since expanded it to 152 genes in order to boost the clinical utility to about 83 percent, from around 65 percent. The company plans to publish a validation study of its test in a peer-reviewed journal in the near future.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.