Thermo Fisher Scientific Immune Repertoire Assays for Hemato-Oncology Research
Thermo Fisher Scientific has launched a new suite of research-use-only Ion Torrent Oncomine immune repertoire assays designed to detect potentially malignant clones of T cells and B cells. Using Ion AmpliSeq technology, the new Oncomine pan-clonality assays target multiple parts of the B- and T-cell immune receptors using a single reaction with ultra-high sensitivity, increasing the probability of malignant clone detection and decreasing time to results.
The new assays also overcome the challenge presented by current next-generation sequencing-based immune repertoire analysis of having to run multiple secondary tests due to the high test-failure rates, Thermo Fisher said. The assays uniquely target multiple parts of the receptor to reduce the need for secondary tests and increase the probability that a single assay can detect a potentially malignant clone.
The new suite of immune repertoire assays is available on the Ion GeneStudio S5 System and feature integrated analysis and data visualization tools that simplify the interpretation of results for laboratories and healthcare professionals, the company said.
Paradigm4 Reveal: Multi-Omics
Paradigm4 has introduced Reveal: Multi-Omics, an app to help biopharmaceutical companies manage and analyze large sets of multiomic data. Reveal: Multi-Omics, built on top of the bioinformatics firm's SciDB database management platform, facilitates cross-study analyses and through rapid searches for genes and proteins across multiple public and proprietary datasets. The new app is an extension of Reveal, a translational informatics platform that Paradigm4 released in 2018.
Applied Cells Mars Mag Cell Isolation Products
Santa Clara, California-based Applied Cells has released its Mars Mag product line for applications on the company's Mars sample preparation and cell isolation platform. Mars Mag are flexible magnetic labeling products that can isolated a wide range of cell types with high purity, recovery, and reproducibility, the company said. They include Mars anti-phycoerythrin magnetic nanobeads that reduce per-experiment cost and enable flexible and easy protocols for capturing and purifying any subpopulation of PE-labeled cells, the company said. The products are intended to improve cell enrichment in tumor biology, genomics analysis, and cell therapeutic development.
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