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New Products Posted to GenomeWeb: Thermo Fisher, Guardant Health, EmpowerDx, More

Thermo Fisher Invitrogen TrueTag Donor DNA Kits 

Thermo Fisher Scientific has launched Invitrogen TrueTag Donor DNA kits for cell line engineering with CRISPR-Cas9 or TALEN technology. They allow researchers to enrich tagged cells and skip clonal isolation. The kits support four types of locus-specific knock-in templates and feature a one-step PCR workflow. They come with integrated Invitrogen TrueDesign Genome Editing software.

Guardant Health Shield 

Guardant Health has launched Shield, the company's first blood-based test for the detection of early-stage colorectal cancer. The test is performed on a simple blood draw sample and is intended for adults age 45 and older who are not up to date with recommended screening guidelines, show no symptoms, and are at average risk for CRC. In a 300-patient validation, the test showed 91 percent sensitivity, including 90 percent sensitivity for Stage I, 97 percent for Stage II, and 86 percent for Stage III cancers, and 20 percent sensitivity for advanced adenomas, with 92 percent specificity.

EmpowerDx Celiac Risk Gene Test 

EmpowerDx has launched its at-home Celiac Risk Gene Test, which uses mouth swab samples to analyze three human leukocyte antigen markers that may indicate the disease. The test is $199 and results are returned 10 business days after sample receipt. The molecular testing is performed by Eurofins Donor & Product Testing.

For more new products and services, please visit the New Products page on our website.

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.