Thermo Fisher Scientific Proteome Discoverer 3.0 Plus MSAID CHIMERYS
Thermo Fisher Scientific and proteomics artificial intelligence software developer MSAID have combined the Thermo Scientific Proteome Discoverer 3.0 software with MSAID's CHIMERYS software to substantially enhance the identification rate and number of unique peptide identifications in proteomics data.
CHIMERYS uses artificial intelligence to identify a minimal set of peptides that can explain the acquired tandem mass spectrum, in comparison to existing methodologies, which typically assume all peaks in a tandem mass spectrum are derived from a single peptide, Thermo Fisher said. This approach provides a 1.8-fold increase in the number of unique peptide identifications and a 1.5-fold increase in the number of protein identifications for typical proteomics data sets when compared to existing tools. In addition to improved protein coverage and quantitation capabilities, Proteome Discoverer 3.0 software paired with CHIMERYS also facilitates faster data acquisition for increased sample throughput.
The Proteome Discoverer 3.0 software release also includes an updated INFERYS prediction model, extending support to tandem mass tagging, collisionally induced dissociation, and providing improved results for immunopeptidomics.
Genialis has launched ResponderID, an artificial intelligence/machine learning-enabled platform for use in clinical biomarker discovery. ResponderID defines, models, and validates new biomarkers for drug development and discovery programs. The platform is a technology suite for clinical and translational research that incorporates proprietary tools for feature selection, data harmonization, and machine learning modeling. While ResponderID can complement virtually any data-analysis environment, it is typically powered by data from Genialis Expressions, the company's FAIR-inspired data management and bioinformatics processing software suite.
908 Devices ZipChip CE-MS Device Oligo Kits
908 Devices announced the ZipChip Oligos assay kit for the company's ZipChip device. The kit provides users with a rapid and simple means of obtaining high-resolution separation and mass spec data from a wide range of oligonucleotides. The kit features orthogonal separation to liquid chromatography, mass identification and quantitation with CE-MS, and analysis within minutes with minimal sample prep and method development, all without the need for ion-pairing reagents.
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