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New Products Posted to GenomeWeb: Tempus, Active Motif, Immudex, Zymo Research, More

Tempus xG

Tempus has launched a new germline sequencing assay, xG, a 52-gene panel that specifically identifies genetic variants associated with hereditary cancer syndromes and inherited risk of cancer. The test is performed by BioReference Laboratories' subsidiary GeneDx and joins Tempus' existing suite of oncology-focused testing offerings, including tumor and liquid biopsy tests, HRD, and TO (tumor of unknown origin) assays.


Active Motif Hi-C Epigenetic Service

Active Motif has launched an end-to-end Hi-C service built on Arima Genomics' Hi-C kits. Hi-C is used by the research community and multiple large consortia such as ENCODE and 4D Nucleome to investigate how genome folding and misfolding impacts gene accessibility, regulation, and expression, and its impact on disease states. Under an agreement with Arima, Active is launching its Active Motif Epigenetic Service to serve academic, pharma, and clinical researchers.


Immudex dCode Dextramer (RiO) Reagents for BD Rhapsody System

Danish life sciences firm Immudex has launched dCode Dextramer (RiO) reagents for use with Becton Dickinson's BD Rhapsody single-cell analysis system. The new reagents are DNA-barcoded versions of the company's MHC Dextramer reagents, and are designed for the identification of many different T-cell specificities in the same sample. The technology directly detects disease-specific T cells based on TCR recognition and DNA barcode labels.


Zymo Research COVID-19 Variant Sequencing Service

Zymo Research has launched its COVID-19 Variant Sequencing Service. The workflow consists of sample collection from testing centers, automated RNA extraction using KingFisher Flex robotics, sequencing with Illumina's COVIDSeq NGS workflow including analysis with the Dragen COVIDSeq analysis pipeline, and reporting. The final report includes COVID-19 strain identification, genome sequencing coverage, confirmed mutations, consensus genome, and raw sequence files. Zymo uses its DNA/RNA Shield preservative to inactivate the SARS-CoV-2 virus and stabilize its RNA.


For more new products and services, please visit the New Products page on our website.

The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.