SpeeDx PlexPrime SARS-CoV-2 Genotyping
SpeeDx has launched a SARS-CoV-2 variant analysis assay for research use only. The PlexPrime SARS-CoV-2 Alpha/Beta/Gamma+ assay is a single-well multiplex test designed to detect mutations N501Y, S982A, and E484K in the spike gene of SARS-CoV-2. These mutations are found in the Alpha (B.1.1.7), Beta (B.1.351), and Gamma (P.1) variants of concern. The test is compatible with standard qPCR instrumentation. It can potentially reduce the manual process of preparing positive samples for sequence analysis by identifying samples of interest, ultimately reducing turnaround and hands-on time, the company said. The firm also plans to launch a multiplex assay for mutations related to the Delta variant, and is currently assessing other mutations.
Bio-Techne RNAscope HiPlex V2 Assay
Bio-Techne announced the expansion of its Advanced Cell Diagnostics (ACD) RNAscope in situ hybridization technology portfolio with the release of the RNAscope HiPlex V2 assay for formalin-fixed paraffin-embedded (FFPE) and fixed and fresh frozen samples for up to 12 targets.
Bio-Techne developed the RNAscope HiPlex V2 assay to enable deeper understanding of vital gene expression patterns at single-cell resolution, enabling researchers to generate precise gene expression data from 12 targets in FFPE samples and up to 48 targets in fresh and fixed frozen sample types. HiPlex V2 enables direct visualization of the transcript and eliminates the need for difficult bioinformatics methods for analyzing and interpreting scRNA-seq data, the company said.
NuProbe VarTrace MSI qPCR
NuProbe has released VarTrace MSI qPCR, a research-use-only assay for detection of DNA microsatellite instability from tissue or blood specimens. According to the company, its technology is designed to help overcome challenges of MSI qPCR including the unpredictable biochemical and biophysical properties of homopolymers. The VarTrace MSI qPCR assay features a lower limit of detection of 1 percent variant allele frequency.
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