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New Products Posted to GenomeWeb: Qiagen, CareDx, Synthego, More

Qiagen QiaSeq Direct SARS-CoV-2 Kit

Qiagen has launched the QiaSeq Direct SARS-CoV-2 Kit, a viral genome enrichment and library preparation product that the company said significantly reduces library turnaround times and plastics use compared with ARTIC project protocols (primer-based approaches for next-generation sequencing that are considered the gold standard for SARS-CoV-2 genome sequencing). QiaSeq Direct SARS-CoV-2 supports sample multiplexing with up to 768 Dual Molecular Indices, unique markets tagged to molecules in a sample to eliminate downstream analysis errors. Starting from extracted viral RNA, the library prep workflow can be as little as four hours, Qiagen said. In addition, plastics usage can be reduced by as much as 50 percent. Qiagen said the new kit is supported by Qiagen's Digital Insights CoV-2 Insights Service, a cloud-based solution tailored to viral genome analysis, characterization, and reporting.


CareDx European HLA Typing Service

CareDx has launched a research-use-only HLA typing service for customers in Europe out of its next-generation sequencing lab in Stockholm. The CareDx HLA typing service is powered by AlloSeq Tx17 and uses high-resolution hybrid-capture technology to yield a fast turnaround time with no long-range PCR inefficiencies. CareDx said that AlloSeq Tx17 provides over 50 percent more gene content than other commercial NGS solutions, including 11 classical HLA loci as well as HLA-E, -F, -G, -H, MICA, and MICB. A company spokesperson said that the service will be available to customers in the US later this year.


Synthego Eclipse Platform

Synthego has launched Eclipse, a CRISPR-based high-throughput cell engineering platform. The automated platform is cell-type agnostic, optimizes transfection, and provides end-to-end data tracking software. Applications include disease modeling, drug target identification and validation, and cell therapy manufacturing.


For more new products and services, please visit the New Products page on our website.

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.