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New Products Posted to GenomeWeb: Qiagen, Bio-Rad, Twist Bioscience, Watchmaker Genomics, More

Qiagen QiaStat-Dx Analyzer 2.0

Qiagen has launched the QiaStat-Dx Analyzer 2.0 for molecular syndromic diagnostic testing, including version 1.6 of the accompanying software. The upgraded system is powered by the new QiaStat-Dx Operational Module Pro with 64-bit processor and 4 GB of RAM and features a cloud-based remote results application that allows users to view, comment on, and confirm diagnostic test results directly from their desktops and mobile devices. This enables greater flexibility between central and regional labs, Qiagen said. Alternatively, users can view results over a shared network.

The system also features enhanced QiaSphere Insights epidemiology dashboards that enable users to view local and global pathogen epidemiology data from all connected QiaStat-Dx instruments. Additional system upgrades include enhanced instrument responsiveness, automatic software updates and notifications, support for 12 languages, and improved remote system management and security features, Qiagen said.

The QiaStat-Dx system features single-use cartridges with built‑in sample processing and onboard reagents to perform multiplex real-time PCR to detect and differentiate between multiple pathogens in about an hour. Available tests for the system include a meningitis/encephalitis panel that analyzes 15 pathogens simultaneously; a gastrointestinal panel that identifies around 20 clinically relevant bacterial, viral, and parasitic pathogens; and a respiratory SARS-CoV-2 panel that detects more than 20 viral and bacterial pathogens.

Bio-Rad Antibodies for Rare and Circulating Tumor Cell Enumeration

Bio-Rad Laboratories has launched validated antibodies for use with the company's Genesis Cell Isolation System featuring Celselect technology for the enumeration of rare and circulating tumor cells (CTCs). The antibodies are specific to CTC surface markers to enable the sensitive and specific identification of target cell populations, enhancing the study of tumor heterogeneity and disease progression, Bio-Rad said. The Genesis Cell Isolation System is a customizable benchtop solution that uses unbiased size-based cell selection to gently and efficiently capture a wide range of CTCs and other rare cells from liquid biopsy samples. After capture, the enriched cells can be recovered for downstream analysis, or immunostained on-slide, the company added.

Twist Bioscience Human Pangenome Spike-in Exome Panel

Twist Bioscience has launched the Human Pangenome Spike-in Panel for the Twist Exome 2.0. It was developed using data from the Human Pangenome Reference Consortium, which includes individuals from geographically diverse populations. The new panel targets 2.5 Mb of pangenome variants and can be spiked into the Twist Exome 2.0 to cover more than 94 percent of novel pangenome variants that affect coding sequences in the exome.

Watchmaker Genomics Watchmaker mRNA Library Prep Kit

Watchmaker Genomics has launched the Watchmaker mRNA Library Prep Kit. The kit can be used to construct stranded mRNA libraries in under five hours while accommodating RNA input amounts from 2.5 ng to 1,000 ng. Watchmaker also said the product is automatable with on-magnet washes to reduce manual cleanup and handling steps.

10x Genomics Visium HD Spatial Gene Expression Assay

10x Genomics has launched Visium HD, a higher-resolution version of its Visium spatial gene expression assay. Using 2-µm2 gapless tiles to barcode transcripts, the assay enables researchers to measure the whole transcriptome from formalin-fixed paraffin-embedded tissue sections at a single-cell scale. Visium HD can integrate H&E or immunofluorescence images from the same tissue section, while the firm's Space Ranger and Loupe Browser software enables analysis and visualization.

Nucleus Genomics DNA Analysis and Whole-Genome Sequencing Service

Nucleus Genomics has launched its DNA analysis product for personalized genetic risk and health reports. Customers who've previously done microarray genetic testing with other companies can upload their DNA data onto Nucleus' platform to receive greater insights into their genetic risk for diseases like type 2 diabetes and breast cancer. Nucleus also integrates personal and lifestyle factors such as age, cholesterol levels, blood pressure, and BMI into its analysis.

The company is also taking pre-orders for its clinical-grade whole-genome sequencing (WGS) service with plans to begin making these more comprehensive results available in the summer. For a yearly membership fee of $39, members will receive access to new features on Nucleus' platform, as well as new disease reports and, eventually, reports for traits like height and muscle strength. The 30x WGS kit costs $399, the company said.

For more recently launched products and services, please visit the New Products page on our website.